Apple has confirmed that their software products, iTunes, QuickTime, Airport For Windows, Bonjour For Windows, iDisk utility, and AppleWorks for Windows does not work with Windows Vista.
It has been confirmed by some bloggers that they could not play the paid songs ( from iTunes store ) after upgrading to Windows Vista. Apple has advised iPod users “Not to upgrade” their Windows until newer versions of iTunes is released.
More details at : Apple Software versions and Microsoft Windows compatibility
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